gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
IgG1 binding to Env on infected cells engages FcγR-bearing effector cells to mediate ADCC/ADCP (and potentially complement activation), leading to killing of Env-expressing cells.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Binds Env on virions and infected cells; N332-dependent V3-glycan supersite
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05079451
disease_id_num_tar_ref
3796
drug_id_num_tar_ref
10258