gene_symbol
MICB
hgnc_id
HGNC:7091
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
The anti-MICB antibody opsonizes MICB+ tumor cells and directly engages Fcγ receptors on NK cells and macrophages to trigger ADCC/ADCP, while maintaining MICB enhances NKG2D-mediated cytotoxicity.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
NKG2D stress ligand (MHC class I-related)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06328673
disease_id_num_tar_ref
3985
drug_id_num_tar_ref
10756