gene_symbol
CD79B
hgnc_id
HGNC:1699
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
ADC binds CD79b on B cells, is internalized, and releases a cytotoxic payload that disrupts microtubules/DNA and triggers apoptosis; Fc effector functions (ADCC/CDC) may contribute.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-cell surface antigen; component of the B-cell receptor complex
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06008691
disease_id_num_tar_ref
3990
drug_id_num_tar_ref
10769