gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CD20×CD3 bispecific antibodies bridge CD20 on B cells to CD3 on T cells, forming an immunologic synapse that activates T-cell cytotoxicity to kill CD20+ cells via perforin/granzyme (MHC-independent).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-cell surface antigen; target on malignant B cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06008691
disease_id_num_tar_ref
3990
drug_id_num_tar_ref
10770