gene_symbol
CD3E
hgnc_id
HGNC:1674
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
CD3ε on T cells is engaged to recruit/activate T cells; these T cells then kill CD20+ B cells via perforin/granzyme. CD3ε+ cells are not directly targeted or killed.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Component of T-cell receptor/CD3 complex on T cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06008691
disease_id_num_tar_ref
3990
drug_id_num_tar_ref
10770