gene_symbol
CD2
hgnc_id
HGNC:1639
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CD2 antibody binds CD2 on T/NK cells and depletes them via Fc-mediated ADCC and complement-dependent cytotoxicity (with possible apoptosis upon cross-linking).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Blocks CD2–CD58 (LFA-3) interaction and depletes/modulates CD2+ lymphocytes
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06453668
disease_id_num_tar_ref
347
drug_id_num_tar_ref
994