gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Vaccine-expressed HPV16 E7 is presented by APCs to prime E7-specific CD8+ T cells; these CTLs recognize E7 peptides on MHC I of HPV16+ cells and kill them via perforin/granzyme and Fas-mediated apoptosis.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Antigen expressed by recombinant vaccinia vector; presented via MHC I/II
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06508138
disease_id_num_tar_ref
4086
drug_id_num_tar_ref
11026