gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Blinatumomab bridges CD3 on T cells to CD19 on target cells, forming an immune synapse; engaged T cells kill CD19+ cells via perforin/granzyme-mediated cytotoxicity (apoptosis/lysis).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Expressed on B cells; also displayed on CF33-CD19–infected tumor cells (truncated CD19)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06063317
disease_id_num_tar_ref
4123
drug_id_num_tar_ref
11130