gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Unconjugated mAbs bind glioblastoma-specific surface antigens and, via their Fc regions, recruit immune effectors to kill target cells through NK cell–mediated ADCC and complement-dependent cytotoxicity (CDC).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Tumor-associated cell-surface targets selected for GB specificity; intended ADCC/CDC and signaling blockade; specific antigens pending discovery
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05917821
disease_id_num_tar_ref
4126
drug_id_num_tar_ref
11136