gene_symbol
ROR1
hgnc_id
HGNC:10256
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-ROR1 CAR T cells bind ROR1 on target cells, triggering T-cell activation and perforin/granzyme-mediated cytolytic killing.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
extracellular domain on tumor cell surface
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05588440
disease_id_num_tar_ref
4136
drug_id_num_tar_ref
11175