gene_symbol
MUC1
hgnc_id
HGNC:7508
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Antibody binds MUC1 on tumor cells and engages FcγR-bearing effector cells to mediate ADCC and activates complement for CDC, leading to lysis of MUC1-expressing cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Tumor-associated, cell-surface MUC1 on epithelial tumor cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06540066
disease_id_num_tar_ref
4443
drug_id_num_tar_ref
12016