gene_symbol
ITGB2
hgnc_id
HGNC:6155
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
ATG binds CD18 (LFA-1) on T cells and induces complement-dependent lysis and Fc-mediated effector killing (ADCC/phagocytosis), depleting the bound cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
polyclonal mixture
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05669001
disease_id_num_tar_ref
4598
drug_id_num_tar_ref
12437