gene_symbol
HLA-B
hgnc_id
HGNC:4932
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
ATG depletes T cells by binding multiple T‑cell antigens (e.g., CD2/CD3/CD4/CD8) and inducing complement-mediated lysis and Fc-dependent ADCC/phagocytosis; HLA‑B is not the cytotoxic target.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
polyclonal mixture
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05669001
disease_id_num_tar_ref
4598
drug_id_num_tar_ref
12437