gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The bispecific antibody binds CD3 on T cells to engage and activate them, redirecting perforin/granzyme-mediated cytotoxicity against CD19+ B cells; CD3+ cells are not targeted for lysis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Targets the CD3 antigen on T cells; specific CD3 subunit not specified
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06549595
disease_id_num_tar_ref
4654
drug_id_num_tar_ref
12577