gene_symbol
PTPRC
hgnc_id
HGNC:9666
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
ATG contains antibodies that bind CD45 on T cells, leading to complement-dependent lysis, antibody-dependent cellular cytotoxicity via FcγR-bearing effectors, and opsonization/phagocytic clearance.
enzyme_product
On
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06674382
disease_id_num_tar_ref
4724
drug_id_num_tar_ref
12772