gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The mRNA vaccine primes neoantigen-specific CD8+ T cells; these T cells recognize neoantigen peptides presented on MHC I of tumor cells and kill them via perforin/granzyme and Fas–FasL pathways.
enzyme_product
Off
epitope
On
variant
On
isoform
Off
hla_specific
On
gated
Off
other_modifier
Multiple patient-specific neoepitopes presented by MHC class I and II on APCs
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06156267
disease_id_num_tar_ref
4729
drug_id_num_tar_ref
12788