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gene_symbol
ULBP6
binding_type
receptor ligand recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
NKG2D on mRNA-modified CIK cells binds ULBP6 on target cells, triggering cytotoxic degranulation (perforin/granzyme) and Fas–FasL–mediated apoptosis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
NKG2D stress ligand; MHC-unrestricted
trial_id_tar_ref
nct_id_tar_ref
NCT06389305
disease_id_num_tar_ref
4802
drug_id_num_tar_ref
12964