gene_symbol
FAS
hgnc_id
HGNC:11920
binding_type
receptor ligand recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
FasL on mRNA-CIK cells binds Fas (CD95) on target cells, triggering extrinsic apoptosis via Fas–FasL signaling (caspase-8), in addition to perforin/granzyme cytotoxicity.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Death receptor engaged by FasL on effector cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06389305
disease_id_num_tar_ref
4802
drug_id_num_tar_ref
12964