gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The DC vaccine primes and expands neoantigen-specific CD8+ T cells, which recognize the same neoantigen–MHC complexes on tumor cells and kill them via perforin/granzyme release and Fas–FasL–mediated apoptosis.
enzyme_product
Off
epitope
On
variant
On
isoform
Off
hla_specific
On
gated
Off
other_modifier
Somatic mutation–derived tumor-specific peptides presented on MHC class I/II
trial_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06751849
disease_id_num_tar_ref
5036
drug_id_num_tar_ref
13616