gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The DC vaccine primes tumor-specific CD8+ T cells that recognize the MHC I–presented tumor peptides and kill antigen-expressing cells via perforin/granzyme (and Fas–FasL) cytotoxicity, augmented by TH1/IFN-γ signaling.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
CD8+ T-cell epitopes
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05799612
disease_id_num_tar_ref
5135
drug_id_num_tar_ref
13920