gene_symbol
CD3E
hgnc_id
HGNC:1674
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The bispecific engages CD3 on T cells to activate them and redirect cytotoxicity (immune synapse, perforin/granzyme, cytokines) against BCMA-positive myeloma cells; CD3+ T cells are not the killed targets.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
component of T-cell receptor/CD3 complex
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06163898
disease_id_num_tar_ref
445
drug_id_num_tar_ref
1257