gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
IgG1 antibody binds CA19-9 on tumor cells and engages immune effectors via Fc to induce ADCC and activates complement (CDC), leading to lysis of CA19-9–expressing cells.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Glycan (carbohydrate) epitope on cell-surface glycoproteins/glycolipids; also known as carbohydrate antigen 19-9
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06069778
disease_id_num_tar_ref
5179
drug_id_num_tar_ref
14051