gene_symbol
MSLN
hgnc_id
HGNC:7371
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR-engineered NK cells bind mesothelin, activate, and kill target cells via perforin/granzyme-mediated cytotoxicity (with cytokine-mediated effects).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
GPI-anchored cell-surface glycoprotein overexpressed on ovarian epithelial carcinoma
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05856643
disease_id_num_tar_ref
450
drug_id_num_tar_ref
1266