gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CD19 CAR-NK cells bind CD19 on target cells and induce cytotoxicity via degranulation (perforin/granzyme) and death-receptor signaling, causing apoptosis of CD19+ cells.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-cell surface antigen recognized by anti-CD19 CAR scFv on NK cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06010472
disease_id_num_tar_ref
5374
drug_id_num_tar_ref
14623