gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR T cells recognize BCMA on target cells and induce cytotoxicity via perforin/granzyme-mediated lysis and apoptosis, with cytokine-driven T-cell activation/expansion.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface BCMA on malignant plasma cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06659770
disease_id_num_tar_ref
5384
drug_id_num_tar_ref
14652