gene_symbol
TRBV9
hgnc_id
HGNC:12246
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Binding to TRBV9 on T cells engages Fc-mediated effector functions (ADCC/CDC), leading to depletion/killing of TRBV9+ T lymphocytes.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface TCR Vβ epitope on TRBV9+ T lymphocytes
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06333210
disease_id_num_tar_ref
5396
drug_id_num_tar_ref
14683