gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
TILs recognize the tumor-associated peptide–HLA class I complex via native TCRs and directly kill target cells through cytotoxic T-cell mechanisms (perforin/granzymes, and Fas–FasL apoptosis).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Includes differentiation and cancer-testis antigen-derived peptides; CD8+ TCR-restricted pMHC-I
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06566092
disease_id_num_tar_ref
471
drug_id_num_tar_ref
1313