gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
LN-145 TILs recognize the neoantigen peptide–HLA class II complex via their native TCRs and directly lyse target cells through perforin/granzyme release and, in some cases, Fas–FasL–mediated apoptosis.
enzyme_product
Off
epitope
On
variant
On
isoform
Off
hla_specific
On
gated
Off
other_modifier
CD4+ TCR-restricted pMHC-II; longer 12–20 aa peptides
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06566092
disease_id_num_tar_ref
471
drug_id_num_tar_ref
1313