gene_symbol
C1QB
hgnc_id
HGNC:1242
binding_type
receptor ligand recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
TRL345 targets HCMV glycoprotein B and can mediate ADCC/CDC against gB-expressing infected cells; it does not bind Complement component C1q B chain, so cells expressing C1qB are not targeted or killed.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Part of C1q complex that binds IgG1 Fc to activate complement
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05408091
disease_id_num_tar_ref
5647
drug_id_num_tar_ref
15343