Skip to main content
gene_symbol
C1QC
hgnc_id
HGNC:1245
binding_type
receptor ligand recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The antibody binds HCMV gB on infected cells and recruits Fc-mediated ADCC and complement (C1q) to lyse those infected cells. C1q (C1q C chain) is only a recruited complement component, not the antigen; cells expressing C1q are not directly targeted or killed.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Part of C1q complex that binds IgG1 Fc to activate complement
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05408091
disease_id_num_tar_ref
5647
drug_id_num_tar_ref
15343