gene_symbol
ULBP4
binding_type
receptor ligand recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
NK receptor–based CAR T cells recognize the NKG2D ligand ULBP4, activating T-cell signaling and cytolytic degranulation (perforin/granzymes) to kill the target cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Stress-induced NKG2D ligand (also known as RAET1E)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05976906
disease_id_num_tar_ref
5750
drug_id_num_tar_ref
15629