gene_symbol
GPRC5D
hgnc_id
HGNC:13310
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
The bispecific antibody binds GPRC5D on target cells and CD3 on T cells, crosslinking them to form an immunologic synapse and activate T-cell killing via perforin/granzyme-mediated apoptosis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Multiple myeloma tumor antigen (product-specific)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06377059
disease_id_num_tar_ref
5814
drug_id_num_tar_ref
15795