gene_symbol
FOLR1
hgnc_id
HGNC:3791
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
ADC binds FOLR1 on tumor cells, is internalized, and releases a cleavable tubulin/microtubule‑inhibiting payload, causing mitotic arrest and apoptosis of FOLR1-positive cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface GPI-anchored receptor; antibody component target
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06238687
disease_id_num_tar_ref
5906
drug_id_num_tar_ref
16017