gene_symbol
FOLH1
hgnc_id
HGNC:3788
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
The anti-PSMA antibody delivers 177Lu beta radiation to PSMA-expressing cells, causing localized ionizing radiation–induced DNA damage (including double-strand breaks) leading to cell death (with some crossfire to nearby cells).
enzyme_product
On
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT04876651
disease_id_num_tar_ref
6059
drug_id_num_tar_ref
16417