gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
The bispecific antibody bridges CD3 on T cells to CD20 on target cells, forming an immune synapse that activates T cells to kill the CD20+ cells via perforin/granzyme-mediated cytolysis (MHC-independent).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Tumor (B-cell) arm target
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06202885
disease_id_num_tar_ref
6155
drug_id_num_tar_ref
16680