gene_symbol
CD3E
hgnc_id
HGNC:1674
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Polyclonal antibodies bind CD3 on T cells and deplete them via complement-dependent cytotoxicity, Fc-mediated ADCC, and induction of apoptosis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
TCR–CD3 complex subunit
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05735717
disease_id_num_tar_ref
6193
drug_id_num_tar_ref
16789