gene_symbol
CD4
hgnc_id
HGNC:1678
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Rabbit anti-thymocyte globulin binds CD4 on T cells, opsonizing them and inducing complement-dependent lysis, Fc-mediated ADCC by NK/macrophages, and apoptosis, leading to direct depletion of CD4+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
T-cell co-receptor
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05735717
disease_id_num_tar_ref
6193
drug_id_num_tar_ref
16789