gene_symbol
CD8B
hgnc_id
HGNC:1707
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Polyclonal anti-thymocyte antibodies bind CD8 (including the beta chain) on T cells, triggering complement-dependent cytotoxicity and Fc-mediated ADCC, and can also induce apoptosis, depleting CD8+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
T-cell co-receptor subunit
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05735717
disease_id_num_tar_ref
6193
drug_id_num_tar_ref
16789