gene_symbol
ITGAL
hgnc_id
HGNC:6148
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Rabbit anti-thymocyte globulin contains antibodies that bind adhesion molecules such as CD11a on T cells, triggering complement-dependent lysis, Fc-mediated ADCC, and apoptosis to deplete the cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
integrin alpha-L (LFA-1) adhesion molecule
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05735717
disease_id_num_tar_ref
6193
drug_id_num_tar_ref
16789