gene_symbol
HLA-DPB1
hgnc_id
HGNC:4940
binding_type
receptor ligand recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The vaccine primes neoantigen-specific T cells; CTLs kill cells presenting the specific neoantigen peptide on MHC, not cells merely expressing HLA-DP (MHC II) itself.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Peptide loading on APCs; primes CD4+ T cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05153304
disease_id_num_tar_ref
534
drug_id_num_tar_ref
1474