gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Neoantigen peptides presented by dendritic cells activate TCRs on CD8+ T cells, which then kill tumor cells presenting the neoantigens via perforin/granzyme; TCR-expressing T cells are activated, not targeted for killing.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Recognizes patient-specific peptide–MHC complexes
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05153304
disease_id_num_tar_ref
534
drug_id_num_tar_ref
1474