gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Elranatamab bridges CD3 on T cells to BCMA on target cells, activates TCR signaling, forms an immune synapse, and induces perforin/granzyme-mediated lysis of BCMA+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Receptor on malignant plasma cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06569147
disease_id_num_tar_ref
553
drug_id_num_tar_ref
1528