gene_symbol
CD3E
hgnc_id
HGNC:1674
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Elranatamab binds CD3 on T cells to activate and redirect them to kill BCMA+ plasma cells via immune synapse formation and perforin/granzyme release; CD3+ T cells are effectors, not targets.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Epsilon chain of the TCR/CD3 complex
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06569147
disease_id_num_tar_ref
553
drug_id_num_tar_ref
1528