gene_symbol
CD7
hgnc_id
HGNC:1695
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CD7-targeted CAR-T cells bind CD7 on target cells, triggering CD3z/4-1BB signaling and killing via perforin/granzyme-mediated lysis and apoptosis (and death-receptor pathways).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06720324
disease_id_num_tar_ref
583
drug_id_num_tar_ref
1637