gene_symbol
TM4SF1
hgnc_id
HGNC:11853
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
ADC binds TM4SF1, is internalized, and releases a cytotoxic payload inside TM4SF1-expressing cells, causing cell death (e.g., apoptosis).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface tetraspanin-like protein enriched on tumor cells and tumor-associated endothelial cells; internalizing ADC target
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06440005
disease_id_num_tar_ref
637
drug_id_num_tar_ref
1784