gene_symbol
CD28
hgnc_id
HGNC:1653
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Polyclonal anti–T-cell IgG binds CD28 on T cells and induces complement-dependent cytotoxicity, Fc-mediated ADCC, and apoptosis, depleting CD28+ cells.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
polyclonal; repertoire varies by product/lot
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06571825
disease_id_num_tar_ref
654
drug_id_num_tar_ref
1833