gene_symbol
ICAM1
hgnc_id
HGNC:5344
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Antithymocyte globulin binds multiple T‑cell antigens (not ICAM‑1) and depletes T cells via complement-dependent cytotoxicity, ADCC, and apoptosis; ICAM‑1–expressing cells are not directly targeted or killed by the drug.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
polyclonal; repertoire varies by product/lot
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06571825
disease_id_num_tar_ref
654
drug_id_num_tar_ref
1833