gene_symbol
HLA-C
hgnc_id
HGNC:4933
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Antithymocyte globulin binds multiple T‑cell surface antigens (not HLA-C) and depletes T cells via complement-dependent cytotoxicity, ADCC, and apoptosis; HLA-C–expressing cells are not directly targeted.
enzyme_product
Off
epitope
On
variant
On
isoform
Off
hla_specific
On
gated
Off
other_modifier
polymorphic antigen
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06571825
disease_id_num_tar_ref
654
drug_id_num_tar_ref
1833