gene_symbol
F3
hgnc_id
HGNC:3541
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
The ADC binds Tissue Factor (CD142) on the tumor cell, is internalized, and releases an intracellular cytotoxic payload that kills the cell (e.g., via microtubule disruption or DNA damage–induced apoptosis).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface TF on tumor cells and tumor-associated vasculature
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06597721
disease_id_num_tar_ref
83
drug_id_num_tar_ref
213