gene_symbol
MET
hgnc_id
HGNC:7029
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
ADC binds MET on target cells, is internalized, and releases a topoisomerase I inhibitor payload that causes DNA damage leading to apoptosis/cell death.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface receptor targeted by antibody component
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06614192
disease_id_num_tar_ref
84
drug_id_num_tar_ref
214